Charting age-associated cognitive decline

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Age-associated cognitive decline.

INTRODUCTION Age-associated cognitive decline-or normal (non-pathological, normative, usual) cognitive ageing-is an important human experience which differs in extent between individuals. The determinants of the differences in age-related cognitive decline are not fully understood. Progress in the field is taking place across many areas of biomedical and psychosocial sciences. AREAS OF AGREEM...

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Age-associated cognitive decline in healthy old people.

BACKGROUND disease often confounds the identification of risk factors for age-associated cognitive decline in elderly subjects. If the cognitive effects of ageing are to be distinguished from those of disease, healthy people need to be studied. METHODS we examined the effects of incident disease and drug prescription on cognitive change in a sample of initially healthy old people in a longitu...

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Neuroanatomical substrates of age-related cognitive decline.

There are many reports of relations between age and cognitive variables and of relations between age and variables representing different aspects of brain structure and a few reports of relations between brain structure variables and cognitive variables. These findings have sometimes led to inferences that the age-related brain changes cause the age-related cognitive changes. Although this conc...

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When does age-related cognitive decline begin?

Cross-sectional comparisons have consistently revealed that increased age is associated with lower levels of cognitive performance, even in the range from 18 to 60 years of age. However, the validity of cross-sectional comparisons of cognitive functioning in young and middle-aged adults has been questioned because of the discrepant age trends found in longitudinal and cross-sectional analyses. ...

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2017

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.171295